LINUS PAULING VIDEOS

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sábado, diciembre 15, 2007

LINUS PAULING: VIDEO CLIPS

Video Clips de Linus Pauling

Interview with Linus Pauling. 1960

Courtesy of the National Film Board of Canada. 16 mm film.

Pauling's interest in sickle cell anemia. Pauling's interest in sickle cell anemia.
Narrator asks how Pauling got interested in sickle cell anemia and they discuss antibodies, Landsteiner, molecular disease, stickiness and clamping, Castle, Itano, Singer, Wells, and reactions to finding the first molecular disease. (4:52) Watch Video
The genetics of disease, a new field. The genetics of disease, a new field.
Narrator asks about mental disease. Pauling mentions sickle cell anemia got him into a new field, genetics of diseases, bad and good genes. (4:53) Watch Video
Broader implications of molecular diseases. Broader implications of molecular diseases.
Narrator asks, "What are the broader applications of molecular diseases?" Pauling replies that a better general understanding can be gained from this knowledge. They can now move in a straight-forward manner to attack therapy for disease. Also discusses phenylketonuria and his studies. (2:34) Watch Video
Future of enzyme research and treatments. Future of enzyme research and treatments.
Pauling mentions giving the Edsel Ford Lecture and his statements about the "Future of Enzyme Research." (1:23) Watch Video
Problems raised by medical research. Problems raised by medical research.
Marriage and children, what's the parent's obligation? Pauling discusses germ plasm deterioration, mutagenic effects caused by X-rays and radiation. He believes that society must attack this problem. Narrator asks about Aldous Huxley's Brave New World, to which Pauling replies that he thinks the bad genes can be dealt with without changing other aspects of people. (5:49) Watch Video
Scientists and moral implications of their work. Scientists and moral implications of their work.
Pauling states that scientists have a greater obligation than non-scientists to discuss the moral implications of their work and to work along social and political lines. (1:39) Watch Video

The Life and the Structure of Hemoglobin. 1976

Produced by the American Institute of Physics. Reel 250. VHS video tape. Running time: 30 minutes.

Magnetic testing of hemoglobin with Charles Coryell. Magnetic testing of hemoglobin with Charles Coryell.
Magnetic test of cow hemoglobin done by Pauling and Charles Coryell. They used an apparatus with a balance and passed electric current through the blood to further determine the structure of hemoglobin. (1:52) Watch Video

NOVA: Linus Pauling, Crusading Scientist. 1977

Sickle cell anemia as a molecular disease. Sickle cell anemia as a molecular disease.
Pauling talks about his work on hemoglobin and his realization of sickle cell anemia as a molecular disease. (2:02) Watch Video

Origins of Molecular Biology and Molecular Medicine. May 20, 1986

University of Alabama-Birmingham. Medical Television, Birmingham, Alabama.

Rockefeller funding to look at hemoglobin. Rockefeller funding to look at hemoglobin.
Pauling talks about his thoughts on hemoglobin and his communication with the Rockefeller Institute regarding further financial support for looking into the magnetic properties of hemoglobin. (1:37) Watch Video
Working on proteins with Alfred Mirsky. Working on proteins with Alfred Mirsky.
Pauling describes his work with Alfred Mirsky on the handling of proteins, the purification of hemoglobin and later their paper which outlined native and denatured proteins. (1:22) Watch Video
Working with Karl Landsteiner on immunochemistry. Working with Karl Landsteiner on immunochemistry.
Pauling recalls meeting Karl Landsteiner, who discovered the blood groups, at Cornell and receiving an intensive course in immunochemistry from him. He then talks about how this influenced his understanding and his own ideas. (1:43) Watch Video
Bill Castle's reactions to sickle cell anemia. Bill Castle's reactions to sickle cell anemia.
Pauling talks about first talking about sickle cell anemia with Bill Castle and his initial reactions. (2:05) Watch Video
Initial tests of hemoglobin by Harvey Itano. Initial tests of hemoglobin by Harvey Itano.
Pauling talks about working with Harvey Itano on testing different kinds of hemoglobin to observe their differences. Also discusses the number of different human hemoglobins reported so far. (2:20) Watch Video
Protein patterns of different species' hemoglobins. Protein patterns of different species' hemoglobins.
Work with Emile Zuckerkandl who ran protein patterns of hemoglobin of different species. Also talks about the evolutionary molecular clock. (4:11) Watch Video
Defining orthomolecular medicine. Defining orthomolecular medicine.
Pauling talks about defining orthomolecular medicine and then states his new direction to avoid directly competing with Harvey Itano. (0:38) Watch Video
Appropriate amounts of vitamin C for humans. Appropriate amounts of vitamin C for humans.
Talk about appropriate amounts of vitamin C for humans and how due to evolution humans don't produce their own vitamin C. (5:21) Watch Video

"The Impact of Linus Pauling on Molecular Biology." February 28, 1995

Talk by Francis Crick at the Linus Pauling Symposium.

Nature article by LP excites Francis Crick. Nature article by LP excites Francis Crick.
Francis Crick tells how an LP article in Nature about sickle cell hemoglobin got him excited about working on molecular problems of genes. (3:53) Watch Video


--
AHANAOA A. C.
Lic. Nut. Miguel Leopoldo Alvarado
http://www.nutriologiaortomolecular.org/
http://www.seattlees.com/

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